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First Oral GLP-1 for Obesity Approved December 2025 In December 2025, the FDA approved an oral formulation of Wegovy (semaglutide) for chronic weight management the first oral GLP-1 to treat obesity

rbmojournal.com Weight Loss Benefits of GLP-1 Receptor Agonists: Studies have shown that GLP-1 receptor agonists significantly reduce body weight and fat mass, contributing to improved metabolic profiles in PCOS patients