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Nausea ranks as the most common early side effect, reported in approximately 25 to 40 percent of patients during the first week

Further development of such peptide inhibitors toward a lead therapeutic candidate, if proven to be selective for the target and relatively free of clinical side effects, may eventually lead to novel treatments for neurodegenerative disorders ranging from Alzheimers disease to Frontotemporal dementia to Parkinsons disease, says Stuart Lipton, a professor of neuroscience at Scripps Research, who was not involved in the study

doi: 10.3109/10715769409147509

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