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Beyond structural membrane functions, this pathway supports biosynthesis of coenzyme Q10 (CoQ10) and glutathione peroxidase 4 (GPX4), both of which contribute to suppression of lipid peroxidation [67]

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For patients experiencing significant symptoms, temporarily pausing therapy, maintaining the current dose for an additional 2-4 weeks before advancing, or implementing smaller dose increments when formulation allows, may improve tolerance

Potential Side Effects and Digestive Changes The most common adverse effects of Wegovy involve the gastrointestinal system, with nausea, diarrhoea, vomiting, constipation, and abdominal pain reported in clinical trials, as detailed in the MHRA-approved SmPC

The second, and most crucial, step came through a strategic partnership