Behavioral intervention for the treatment of obesity: strategies and effectiveness data
In high school, Cayman, now a medical researcher, gained around 80 pounds in just three months, partly due to her polycystic ovary syndrome
Additionally, side effects of GLP-1 medications, like nausea and vomiting, can prompt dehydration (and dry mouth), enamel erosion, tooth sensitivity, and discoloration
Recommended monitoring protocol: Baseline: Full thyroid panel (TSH, free T4, free T3, TPO antibodies, thyroglobulin antibodies) plus thyroid ultrasound before starting GLP-1 therapy 6-8 weeks after starting GLP-1: Recheck TSH and free T4
Despite these beneficial metabolic effects, native GLP-1 has significant pharmacokinetic limitations that restrict its therapeutic utility