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The authors KK, KR declared that they were an editorial board member of Frontiers at the time of submission

With experience as a hospitalist, she brings a strong clinical foundation shaped by work in hospitals and nursing homes, offering a broad perspective on patient care across diverse settings

Gastrointestinal issues: Its common for patients to experience stomach problems, including nausea, diarrhea, or constipation

doi: 10.3389/fendo.2025.1568059 Received 28 January 2025 Accepted 10 April 2025 Published 30 April 2025 Volume 16 - 2025 Edited by Joao Dts Anselmo, Hospital do Divino Esprito Santo, Portugal Reviewed by Lucile Butruille, Musum National dHistoire Naturelle, France Updates Copyright 2025 Khudair, Khudair, Niinuma, Habib and Butler

Niacinamide (vitamin B3) may provide additional metabolic support, though the evidence base for this specific combination is still developing