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[10] SURMOUNT-1 : Tirzepatide for the treatment of obesity produced ~2022% weight loss over 72 weeks, among the largest effects seen in pharmacologic obesity treatment

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In the UK alone, a report has suggested that the grocery market has lost an estimated 136 million, driven by GLP1 users cutting their food and drink spending by around 2% more than non-users (36)

Moreover, GLP-1R expression has also been detected in several components of the immune system, such as macrophages, lymphocytes, and invariant natural killer T (iNKT) cells (Song et al., 2017)