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Chronic straining from constipation puts repeated downward pressure on the pelvic floor, increasing the risk of stress incontinence, urge incontinence, and in more significant cases, pelvic organ prolapse

doi: 10.2337/db19-1004-P 46 MosenzonO.WiviottS

One study called the prevalence of optimal metabolic health alarmingly low, with only one in eight adults meeting the criteria

The metabolic regulation and vesicular transport of GLUT4, the major insulin-responsive glucose transporter