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doi: 10.1016/J.REPROTOX.2023.108531 21

Clinicians managing complex cardiometabolic cases should individualize treatment decisions

However, as with any skincare ingredient, it is advisable to perform a patch test before using a new product to ensure there are no adverse reactions

: KLOW : FAQ 1

6 In obesity without diabetes (a 72-week trial, ~3,127 participants), mean body-weight change reached roughly 7.5%, 8.4%, and 11.2% at 6, 12, and 36 mg versus about 2.1% with placebo on the treatment-regimen estimand, with the highest dose reaching approximately 12.4% (about 27 lb) on the efficacy estimand, accompanied by improvements in cardiometabolic risk markers