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This efficacy/security gap suggests that orforglipron is unlikely to significantly erode the market share of subcutaneous formulations

A patient may react to a dye, preservative, filler, or adhesive in a commercial product

There are also several positives for PA patients from the 2024 NICE guidelines The guidelines emphasis on a symptom-based approach to treatment is an urgent and necessary shift that could positively influence current practice

As understanding of GLP-1 biology deepens, so too does the potential to tailor therapies for specific disease pathways