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The 5 Clinical Stages opt-out exclusionary screen : end-stage kidney disease, end-stage liver disease (cirrhosis), current suicidal thoughts and prior suicide attempt, active cancer treatment or recent cancer-free history, organ transplant on anti-rejection meds, severe GI conditions (gastroparesis, blockage, IBD), and current alcohol/opioid/substance use disorder

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Registered dietitian Paige Smathers explained that GLP1s have sparked divided opinions in the nutrition field

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Managing Injection Discomfort and Minimizing Bruising Cold skin reduces sensation before injection, so applying a cold compress or ice pack to the injection site for 30-60 seconds before needle insertion can lower perceived pain