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From baseline until 1 week after the last dose of randomised treatment, a total of 13 participants (3.8%) in the IcoSema group and 71 participants (20.8%) in the semaglutide group initiated non-randomised insulin or additional non-insulin glucose-lowering medications for more than 2 weeks, with most of them initiating oral glucose-lowering medications rather than insulin treatment

Liposomes protective effect has been attributed to their amphiphilic structure, which facilitates interaction with the skins lipid bilayer and improves the transport and release of antioxidants directly into affected cells [62]

states and territories had an obesity prevalence of more than 20%