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Oocytes containing both female and male pronuclei (regardless of the stage of decondensation) relative to the total number of oocytes that matured were considered fertilized and were classified as normal (2PN) according to the numbers of swollen sperm heads and pronuclei in the cytoplasm

Because of these differences, Contrave may be combined with other treatments in select cases when medically appropriate, especially for patients who need both physiologic appetite reduction and behavioral craving support

Surg Today 2008