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In the screen against the glutathione-deficient yeast strain (Screen I), where any compound inhibiting ChaC1 would permit the growth of these cells (greater than three times the standard deviation of the mean library effect), were considered for further evaluation (Table S2)
Clinical trials have demonstrated the efficacy of GLP-1 medications in achieving significant weight loss
It also supports immune function by helping white blood cells stay resilient
Perhaps the people who weren't taking GLP-1s had other health issues, like depression or kidney disease, impacting their chance of survival
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