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CervantesAAdamRRosellSArnoldDNormannoNTaebJet alMetastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

GLP-1 receptors in the brain The brain contains abundant GLP-1 receptors in key regions including the hippocampus, cerebral cortex, hypothalamus, thalamus, and globus pallidum 26

For drugmakers, the news reinforces the need for a more focused pipeline strategy, optimizing and expanding in areas where GLP-1s are already validated, like weight management, cardiovascular risk reduction, and liver disease