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Beyond classical antioxidant signaling, GSH interfaces with additional pathways, including Hippo-Yes1 associated transcriptional regulator (YAP1) signaling to regulate GPX4 and SLC7A11 expression, 159,160 mechanistic target of rapamycin kinase (mTOR) signaling to influence GPX4 protein synthesis through cysteine metabolism, 161 and NF-B signaling to restrain inflammation-associated ROS production 162
Additionally, its role in the formation of new blood vessels highlights its potential for acute injuries and muscle growth
Riboflavin-5-Phosphate (Active Vitamin B2) Supports mitochondrial energy production, antioxidant pathways, and nervous system function
& Shoback, D
Bubna AK
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