Human CYP1A2, CYP3A4 proteins purified as a microsomal formulation containing cytochrome b 5 and cytochrome P450 reductase were obtained from Sigma (C1561 and C4982, respectively)
Kjller R, Cruz-Paredes C, Clemmensen KE
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A key regulator of NRF2 activity is kelch-like ECH-associated protein 1 (KEAP1), which acts as a ROS sensor and principal suppressor of NRF2