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Endocrinology 144:32443250 Roberge JN, Brubaker PL (1993) Regulation of intestinal proglucagon-derived peptide secretion by glucose-dependent insulinotropic peptide in a novel enteroendocrine loop

For example, if a patient experiences severe abdominal pain, this could indicate a more serious condition like pancreatitis, which is a rare but possible side effect of these medications

Gut microbial dysbiosis alters regulatory T cells (Tregs) and cytokine balance, perpetuating inflammatory pathways even in the absence of overt infection

it is not yet FDA-approved as a standalone medication

Data from small studies suggest preconception GLP-1 use may help improve pregnancy odds in this patient population