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While the comproportionation reaction is a well reported redox cycling chemical mechanism, in this instance the triad model does not require the additional comproportionation reaction to accurately replicate the experimental OCR profile, suggesting that the comproportionation reaction is not mechanistically integral to the production of ROS through a quinone-based redox cycle

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LUXendin-645 imaging To assess access of GLP-1R antagonists to the olfactory bulb from the circulation, awake PPG-YFP mice ( n = 3) were injected subcutaneously with 30 nmol/kg LUXendin645 at a dose volume of 1 ml/kg

More studies will be needed to confirm these hypotheses and better understand how LGP-1 achieve this benefit

Physio., 581(pt2), 431-444, 2007