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My go-to collagen supplement is Amandean Marine Collagen

AMPK activation causes cells to utilize their stored fuel more efficiently, improving insulin sensitivity and glucose uptake into muscles

MSU crystals directly enhance CD18 integrin activation in neutrophils (79), augmenting their ability to migrate toward these crystals via leptin-facilitated mechanisms (45)

Clinical studies show that approximately 70% of weight loss returns within 12 months after discontinuing GLP-1 medications like Wegovy, largely because these drugs manage hunger signaling rather than alter underlying metabolic patterns

More recently, the European Society of Cardiology (ESC) has deemed GLP-1 RAs to be the first-line therapy for cardiovascular risk reduction in patients with T2DM with very high/high risk [10]