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[11] In practice, this means that while normal doses are safe, any use of pyridoxine beyond typical supplemental levels during pregnancy should be guided by a healthcare providers assessment of risk versus benefit

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[8] [11] [12] [13] [14] [15] [16] [17] A 1961 report by Paul OHollaren, MD, of Shadel Hospital in Seattle, Washington, led to a study that led to the widespread use of IV infusions of NAD+ for the treatment of addiction