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According to Eli Lillys press release, orforglipron can be taken at any time of the day without restrictions on food and water intake

I havent talked about it publicly until now, because we still havent figured out whether we can bring it to market in a form that actually works

If the diarrhea persists, contact a healthcare provider for potential dose adjustments or follow up. Prioritize rehydration & electrolytes Diarrhea can quickly lead to dehydration

PlexusDx recommends taking your weekly dose fasted, then waiting 30 minutes before eating a full meal

Baseline lab work allows your provider to ensure peptides are appropriate for your needs and to create a customized plan