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Redox Biology 11, 297311

208 Additionally, SIRT3 regulates metabolism by facilitating the deacetylation and activation of isocitrate dehydrogenase 2 (IDH2), a key enzyme in the TCA cycle

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In TCM theory, Salviae miltiorrhizae Radix et Rhizoma is used to invigorate blood circulation, remove blood stasis, relieve pain by dredging menstruation, clear heart fire to relieve restlessness, and eliminate carbuncles