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Common side effects include, but may not be limited to: pain or redness at the injection site mild diarrhea pruritus (itching) increased swelling joint pain dizziness headache nervousness or anxiety Serious side effects may include: allergic reactions peripheral vascular thrombosis hypokalemia (low potassium levels) pulmonary edema (fluid build-up around or in the lungs) thrombocytosis congestive heart failure There have been reports of anaphylactic shock and death after the parenteral administration of vitamin B12

Regulation of the NMDA receptor by redox phenomena: inhibitory role of ascorbate

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Moreover, increased NR3C1 promoter methylation-particularly at the exon 1H region, has been observed in the PFC of individuals with alcohol use disorder, accompanied by reduced NR3C1 mRNA and protein expression 171

GAT1 also clears GABA from the extracellular space