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Drug coupling on 3-PLG and 3-PLG-A-GSH EDC/NHS coupling chemistry was used to couple dopamine and ibuprofen with 3-PLG and 3-PLG-A-GSH (Fig

Additionally, inhibition of CD38 in the AD mouse model restored NAD + levels, decreased mitochondrial ROS production and plaque depositions in the hippocampus and cortex, and improved cognitive abilities 158

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