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Neuropsychopharmacology 32 : 367376

Clearly this could not be done, so, in this example, one has to rely on other types of evidence. Hill and Doll tried to find that evidence in the hospitals of London

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15,690 patients with gout and 246,210 controls were included in that survey, and the overall risk of heart diseases, including ischemic heart disease and heart failure, and the risk of stroke in the gout group were respectively 1.57 (95% CI=1.521.63) and 1.32 (95% CI=1.271.38) times higher than those in the control group (11)