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Routine lipase testing in an asymptomatic person is not a reliable stand-alone screening strategy for pancreatitis

Multiple studies suggest that GLP-1RAs demonstrate significant anti-inflammatory properties across various cell and tissue types, effectively suppressing sustained inflammatory responses during chronic inflammation [94]

Ongoing large-scale prospective studies and post-marketing surveillance are needed to further refine risk estimates and inform evidence-based clinical guidance for patients at higher baseline risk

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This discovery can shift our perception of metabolic health, highlighting chronic low-grade inflammation as a central factor in metabolic dysfunction and a broader array of chronic diseases