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Chronic hyperglycemia exacerbates endothelial damage, reducing endothelial nitric oxide synthase (eNOS) activity, and worsening oxidative stress and inflammation, ultimately impairing penile vascular dilation [72,73,74]

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Compounded GLP-1 Therapies It is important to distinguish between FDA-approved medications and compounded formulations

Given the critical role of GLP-1 in various physiological processes, including its presence in organs such as the pancreas, gastrointestinal tract, and brain, understanding its effects on fetal development has become increasingly important [4]