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If "stronger" means more familiar biology, a clearer bridge from an already-approved GLP-1 backbone, and a less radical product concept, CagriSema looks stronger

Methods: In this prespecified imaging subanalysis of the PRESTIGE-AF trial, we centrally assessed brain CT and MRI scans taken before study enrolment from all included patients using established scales and definitions

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- Kruse Journal Of Medicinal Chemistry In practice, this means Cagrilintide doesnt just make you feel full it creates a sustained reduction in appetite and caloric intake, while also improving glycemic balance, making it a strong candidate for long-term obesity management