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In this review article, we aimed to update the understanding of the possible roles of HDACs in the pathophysiology of epilepsy, discuss the likely regulatory mechanisms of these enzymes and summarize the recent progress in the development of HDACi in epilepsy rodent models and patients
In other words, two studies can list the same dose and still test meaningfully different conditions
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Sumithran P, Prendergast LA, Delbridge E, et al
Each has documented limitations: NSAIDs: Reduce inflammation short-term but inhibit prostaglandin pathways needed for tissue repair
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