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3.4.1 Preclinical evidence Extensive preclinical research supports metformins cardioprotective role in DOX-induced cardiotoxicity (Singh et al., 2022

Regulation of the mitochondrial permeability transition pore by the outer membrane does not involve the peripheral benzodiazepine receptor (TSPO)

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Aim for 6-8 glasses (64 ounces) daily

Doctors prescribe it for specific medical indications, for example, children with poor growth due to low GH, or adults with confirmed GH deficiency causing symptoms