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and HR=0.31, 95% CI 0.26-0.37, respectively) (all p 3.25) (HR=3.24

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195 Considering everything stated before implying cysteine as relevant to sustain the high performance (survival and proliferation) of cancer cells, acting as a detoxifying component or as an energy or biomass source

The combination of GPX4 inhibitors with immune checkpoint inhibitors (ICIs) targeting the PD-1/PD-L1 axis increases the proportion of CD8 + T cells, enhances their cytotoxic activity and induces ferroptosis, thereby promoting chemotherapy resistance [42]

PMID: 24197760