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Pathophysiological processes where melatonin plays important roles Antiapoptotic activity Almost all the studies that monitored the melatonin-dependent antiapoptotic activities include disease models characterized by the presence of a hypoxicischemia (HI) event

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Although the majority of current treatments for DPN are unable to achieve complete neuropathic pain reduction, clinical studies support acetyl-L-carnitine (ALC) as a promising therapeutic agent for DPN

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First, they help to maintain the slow, rhythmic firing pattern by generating an oscillation in the membrane potential