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Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: [The authors declare no conflicts of interest regarding the publication of this article

Scientists have actually taken the time to try and calculate the probabilities of DNA spontaneously forming (of course, one would have to ask where the parts came from and how would it know how to operate assuming the parts spontaneously appeared)

Collagen type I is particularly important because it forms the backbone of the extracellular matrix, supporting dermal strength and elasticity

The hydrolyzed peptides form makes the collagen more easily digestible and absorbable

But since peptide coupling agents are described as immune sensitizers, it stands to reason that the risk even if its small exists for everyone.18 Copper peptide uglies Anecdotal reports suggest that some people may experience worsened skin aging, instead of anti-aging, after using products with GHK-Cu, a rare concern dubbed copper peptide uglies. While this isnt necessarily a safety issue, it is a (again, rare) potential negative effect of using copper peptide products