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GLP-1 agonists should be initially prescribed at the lowest dose and slowly uptitrated to avoid gastrointestinal side effects

Catherine Varney, an obesity medicine physician and associate professor at the University of Virginia School of Medicine who is also part of the Lilly speakers bureau and advisory board

Due to their action profile, they directly affect three types of opioid receptors (MOR), (DOR), and (KOR)

Thats why drugs like GLP-1 agonists have gained popularity for their appetite-suppressing effects, with their use increasing by 111% in the United States between 2020 and 2022

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