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The strategy was, therefore, to identify GLP-1 mimetic drugs with a molecular structure close enough to native GLP-1 to stimulate the GLP-1 receptor, but with alterations that enabled prolonged activity by, in particular, possessing resistance to breakdown by DPP-4 (Meier, 2012)

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A PASI75 was achieved with combination therapy by 97% of those with evaluable skin disease compared with 54% of those receiving methotrexate monotherapy

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Thymosin beta4: actin regulation and more