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In vitro experiments demonstrated that cancer-associated adipocytes upregulate the hexosamine biosynthetic pathway (HBP), leading to O-GlcNAcylation and stabilization of the YAP protein

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This happened in studies like SURPASS-2 and SURMOUNT-1

Moreover, two studies from the same group demonstrated increased duodenal permeability, assessed by CLE, in IBS patients upon perfusion of diluted food antigens (49, 50)

Clin Exp Dermatol 42:614621 Chen PH, Cai L, Huffman K et al (2019) Metabolic diversity in human non-small cell lung cancer cells