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Blood or fluid cannot leak out and damage the macula any further (Wormald 2007)

Rapid weight loss from any cause, including semaglutide, may increase gallstone formation risk in susceptible patients with an intact gallbladder

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26 GLP-1 and effects on bone metabolism Several studies show that the GLP-1R is expressed in some bone cells, including osteoclasts and BMSCs, but appears to be absent in mature osteoblasts, indicating a complex role in bone homeostasis that is incompletely understood