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The SUSTAIN-6 trial measuring semaglutide outcomes reported systolic reductions ranging from 35 mmHg in the overall population, with larger improvements seen in participants who also achieved weight loss

Sample collection After the last weighing, these experimental animals were fasted for 24 hrs with free drinking water

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Both medications reduce appetite through different pathways, and their combined effect might lead to inadequate caloric and nutrient intake, potentially causing muscle loss, vitamin deficiencies, or metabolic complications