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Its enzymatic function is based on two aspects: its catalytic activity and the auto- S -glutathionylation of GST by itself on Cys47 and Cys10, both of which disturb the subsequent interaction with c-Jun NH 2 -terminal kinase (JNK), resulting in the formation of a GST multimer 30 (Figure 3)

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Preclinical models suggest it may: Activate telomerase , an enzyme that supports the extension and maintenance of telomeres in cell culturestructures that protect chromosome integrity during replication

[8] [9] This means that higher oral doses may be required in certain circumstances to achieve therapeutic effects

Rat liver citrate cleavage enzyme