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If your trip exceeds 21 days without reliable refrigeration access, you may need to arrange for a fresh supply at your destination

However, people with normal intestinal absorption and mild to moderate B12 deficiency symptoms can take oral B12 supplementation (B12 and folic acid pills)

According to the NHS, untreated deficiency can affect the nervous system and blood health

This is usually the case for elderly populations, those following a vegetarian or vegan diet, and people with disordered eating or chronic diseases that lead to malnutrition

The clinical trials showed steady weight loss progression through 68 weeks, with the most rapid loss occurring between weeks 8 and 32