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Symptoms often mimic allergic or autoimmune disorders, including: Flushing, itching, hives Gastrointestinal distress Headaches or brain fog Fatigue and anxiety MCAS is frequently underdiagnosed and can overlap with histamine intolerance or chronic inflammatory conditions

J Biol Chem 250:14221426 Riedel G (1996) Function of metabotropic glutamate receptors in learning and memory

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The method is based on an electrochemical detection system using a boron-doped diamond disc (BDD) electrode (Model 5040, ESA Biosciences, Chelmsford, MA, USA)