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Together, the UPR sensors alleviate ER stress by attenuating global protein synthesis to reduce the load of unfolded proteins, increasing chaperone synthesis to guide protein degradation or refolding misfolded proteins, and synthesizing lipids to increase ER volume (29)

Biom J 63, 187-200 (2021)

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Single-Stack System vs Two-Stack System Single-stack systems are common in smaller residential buildings, where one main vertical pipe handles both drainage system functions and venting

Lahiguera , Hyroov P, Figueras A, et al