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The authors of the study concluded: The considerable shortage of dietary creatine is associated with an increased risk of heart and liver conditions, which calls for public measures that foster diets rich in creatine-containing foods, and additional research to investigate the role of creatine in age-related diseases.[ref] Another study found that getting over 0.95g of creatine in foods daily was protective against cognitive decline in older adults.[ref] Clinical trials using creatine supplements: Creatine supplements have been very well studied, with thousands of clinical trials, and looking at the trial results can give us a picture of when and where creatine supplementation is useful

Meetings could also be scheduled if there was a serious AE suspected to be caused by the study, but this did not occur

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Greene MH, Reimer RR, Clark Jr WH, Mastrangelo MJ

others find minimal difference from placebo