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What it feels like An oral melanotic macule is asymptomatic (causing no symptoms)

among those, stronger evidence exists for metabolic disorders, allergies, autoimmune diseases, disturbances of the central nervous system, and some forms of cancer (Fitzgibbon and Mills 2020)

Kaloshi, G

However, the extent to which NRF2 regulates its target genes beyond promoter-restricted regions, and the significance of this regulation to NRF2-dependent cancer cell maintenance, remains unexplored