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Over a 30-day protocol with daily dosing, that single vial gets punctured 30 times, exposed to room temperature 30 times, and receives 30 doses of fresh oxygen

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When estrogen declines, that balance shifts

There are approved GLP-1 and GIP/GLP-1 medications available for specific indications, and there are investigational multi-receptor agonists still being studied

In a first part, I discuss biological issues related to the persistence of microbial antigens, dysregulated immune responses, reactivation of latent viruses, different potential self-sustained inflammatory loops, mitochondrial dysfunction, metabolic disorders in the tryptophan- kynurenin pathway (TKP) with impact on serotonin, and consequences of a dysfunctional bidirectional microbiota-gut-brain axis