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Why GLP-1Related Muscle Loss Is Adaptive Remodeling Not Muscle Wasting All effective weight-loss interventionsdietary, surgical, exercise-based, or pharmacologicreduce both fat and lean tissue to some degree

This is often the preferred site for its ease of access and is generally less painful

Patients who want to track lean mass separately from total weight can discuss DEXA scanning or clinical body composition assessment

However, it is essential to note that when additional pharmacological intervention is required to control diabetes mellitus, the choice between SGLT-2 inhibitors and GLP-1 RAs should be based on the patients individual needs and the specific medications already being used

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