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While there are no absolute dietary restrictions, certain foods commonly worsen gastrointestinal side effects like nausea, bloating, and discomfort
Volcano plots highlighted numerous metabolites that were dysregulated in DM mice and restored by SE treatment (Figures 4B, C)
For instance, methotrexate (MTX) inhibits ENPP1 activity, activates the cGAS-STING pathway, and synergistically enhances the efficacy with radiotherapy and PD-1 inhibitors, significantly improving the partial response rate of patients with esophageal squamous cell carcinoma
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