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Board PG, Taylor MC, Coggan M, Parker MW, Lantum HB, Anders MW

Once obtained, H 2 O 2 can be degraded in mitochondria via the GSH redox system, employing glutathione peroxidases (Gpxs) and GRs, but also through peroxiredoxins (Prxs), a family of thiol-specific peroxidases

Nature 413:171174 Liu H, Wang H, Shenvi S, Hagen TM, Liu RM (2004) Glutathione metabolism during aging and in Alzheimer disease

Hepatic stellate cells support hematopoiesis and are liver-resident mesenchymal stem cells

Levels decline with age and drop further in chronic disease, including Parkinson's disease, liver disease, heart disease, and alcohol use disorder