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On day 3 of each treatment, blood pressure and heart rate were recorded for 24 h using an ambulatory blood pressure monitor (Accutracker, SunTech Industries, Raleigh, North Carolina)

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CCN1 , also known as Cyr61 , was found to be upregulated in lung epithelial cells by CSE via the induction of ROS and endoplasmic reticulum stress, which subsequently resulted in augmented IL - 8 release through the activation of the Wnt pathway [193]