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Specifically, testosterone (the major androgen) mediates sex-biased immune cell functions in natural killer (NK) cells, CD8 + T cells, and neutrophils via AR-dependent genomic and non-genomic pathways, which involves suppressing interferon regulatory factor 8 , activating forkhead box O1 , and modulating T-Box transcription factor 21 at the transcription factor level

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A commenter that supported the proposal also expressed concern that Medicare GME funding may be used to pay for abortions, in violation of the Hyde Amendment, which generally prohibits the use of Federal funding for abortion except under limited circumstances

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